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Cation Effect on Slow Release from Alginate Beads: A Fluorescence Study

Journal of Fluorescence

2014

H. Kaygusuz, F.B. Erim, Ö. Pekcan, G.A. Evingür

TOC

In this study, spherical alginate beads containing pyranine (P y ) as a fluorescence probe were prepared by ionotropic gelation of a sodium alginate solution. The steady state fluorescence technique was used to study pyranine release from the alginate beads crosslinked with calcium, barium and aluminum ions, respectively. The slow release of P y was observed with the time drive mode of the spectrophotometer at 512 nm. Fluorescence emission intensity (I p ) from P y was monitored during the release process, and the encapsulation efficiency (EE) of pyranine from the alginate beads was calculated. The Fickian Diffusion model was used to measure the release coefficients, D sl . It was seen that the slow release coefficients of pyranine from the alginate beads crosslinked with Ca2+, Ba2+, and Al3+ ions increased in the following order: D sl (Al3+)> D sl (Ca2+)> Dsl (Ba2+). In contrast, the initial amount of pyranine and EE into the beads showed the reverse behavior.

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